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Apicore, LLC.
Apicore USA

EQUIPMENT

Process Research:

  • 7 chemical hoods

 Pilot Plant & Small scale API manufacturing:

  • 4 Jacketed glass reactors  1 X 30 Lt. and 3 X 50Lt.
  • Heidol pl. 20 Liter rotary evaporators  & 2L Buchi rotary evaporator (4)
  • Several 12 liter and 22 liter glass reaction assemblies
  • Vacuum Tray driers
  • Lyophilizer
  • Multi-Mill
  • Filtration Units / Centrifuge
  • Neutsche Filter
  • Blender
  • Sieves
  • Purified water system
  • Hydrogenator 

 Analytical Instrumentation:

  • HPLC's [ Waters 2790, 2795, Shimadzu 2010 HT]
  • GC's [ Perkin Elmer Headspace GC(Clarus 500), Shimadzu Headspace GC]
  • LC/MS/MS [ Waters/Micromass Quattro LC]
  • MALLS [Wyatt]
  • NMR [ 500 MHz Varian Inova]
  • GFC [ Perkin Elmer system with RI detector and UV/Vis Detector]
  • CE [ Beckman PE800 Capillary electrophoresis system]
  • FT-IR, UV-Visible spectrometer, Melting & boiling point apparatus, Autotitrators etc
  • Stability Chambers  

  Highly Potent Active Ingredient Suite at Apicore USA

  •  A dedicated HPAI suite was constructed at our Somerset, NJ facility.
  • The suite contains an R&D lab, manufacturing area and QC lab.
  • We have successfully produced our first Anti-Cancer product in this suite and supplied cGMP material to our partner for production of the ANDA batches.
  • This facility is equipped with 50L glass, jacketed reactors and can be used to manufacture batches ranging from 0.5Kg to 5Kg batch sizes.
  • 2L Buchi rotary evaporators
  • 1 Neutshe Filter